My father and his sister are both bipolar, my mother had issues of mania when I was younger and my paternal grandmother has anxiety issues and some agoraphobia. However, she lived in Japan during WWII to we always attributed it more to that. Now I have Bipolar type II, anxiety, mania, PTSD and depression issues. My 4 year old son is showing some signs of being bipolar and manic, but I'm not sure if he could even be diagnosed yet.