if your doc suggests up to 300mgs i'd value her opinion in spite of this quote below. sounds like pdoc is tweaking your dx by adding other rx. see if you respond well to these additions first, imo, and i'm no doc so take this with a grain of thought.
Quote:
11. What is the usual final dose of lamotrigine? When used as an antidepressant or as a mood-stabilizing agent the final dose of lamotrigine is most often between 100 and 200 mg/day. Some people require doses as high as 600 mg/day to achieve a good antidepressant effect. Such doses should be avoided in patients taking valproate because of the pharmacokinetic effect of valproate that increases plasma levels of lamotrigine, and the accompanying increased risk of serious dermatological side effects.
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http://www.psycom.net/depression.cen...motrigine.html
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