I don't know where the idea of precisely what constitutes a "dose" of any of these antidepressants comes from. Why is it that you take 20 mg of Paxil, but an equivalent dose of Effexor is supposedly 150 mg? Why not 150 Paxil, and 20 Effexor? Ya know?

And some drugs metabolize very differently in different people's bodies. I'm very sensitive to medication. Of the drugs I'm using now, my tolerance of two particular drugs is about 1/3 in one case, and 1/10 in another. I just can't come near what the doctor was calling a "therapeutic dose". Toxic dose, for me.

I've heard of some enlightened doctors prescribing their med-sensitive patients the pediatric liquid formulations for e.g. Prozac. Because the dose varies precisely as the volume, if you measure out your medicine carefully, you can get any dose you want. 2.5 mg Prozac a day, precisely, if that's what you want. The pills don't come in anything near that small a dose, and breaking pills is not a good way to measure drug doses.

I'm too sensitive to take regular drug doses. I'm lucky my doctor finally believes me.

Just some random thoughts.

Lar