I'm off meds now and frankly don't miss them at all. Many of them seem to have some subtle, at times short-lived beneficial effect I can't explain, but I prefer to seek other options considering the comparatively significant side effects and unwelcome changes in cognition I have on them. Also, the best one I tried simply stopped working at all, and all the others have been relatively disappointing. The possibility that I have simply been experiencing a placebo effect has occurred to me.

Self-help, reflection and talk therapy have been most beneficial to me overall. I am finding that rooting out old causes for lingering negative thoughts and expectations, and trying to challenge the negative expectations and disrupt the behavioral patterns they cause, is finally producing positive results. I believe that for many, mood disorders are a symptom of something deeper that may express itself biologically, but is sustained by our psychology.