When I was first diagnosed I was on Depakote and I gained 80 lbs ! Now I am on Geodon and I've lost a few pounds but it's hard. I take Zyprexa when I hear voices but I don't take it all the time because my doctor said I'd gain weight. The best thing to do is try to get some exercise I try to go to the YMCA and swim at least 3 times a week, it does make me feel better.