I have been taking sertraline for about seven months. I have noticed a difference. The depression and anxiety have both decreased for me. I usually have pretty bad PMS, though. Today is the first day I have felt depressed in a long time. It's mild but it's there. I had a trigger, due to a financial issue and now I just feel more dejected, tired, sad then I have in a long time. I suspect this is in part due to PMS because the days seem lined up exactly when I would be experiencing it. Anyone have an experience with depression worsening due to PMS? Did you ever increase your AD use during this time? I am going to ask my doc when I see him next. I was just wondering if anyone had ever heard of this.

Thanks. Elana