I gained about five lbs. on seroquel. Not a lot, I was also on supervised eating schedules in the hospital at the time. My worst offender was Zyprexa. But then I have also been on lithium for 6 years and have gained none from that.

Antipsychotics are know to cause metabolic changes amongst other things. I have been dealing with anorexia for years, while on zyprexa I gained 20 lbs in one month. It was like I literally puffed up. As soon as I went off it, I returned to my normal weight within a few weeks. Eating habits had never changed., and I have always been fairly active.

Really the only way to tell is to try it out and see. Everyone is so different, and it could be what you having been looking for.