Are you positive it's the klonapins? Also, how much are you on? I take .5-1mg for anxiety & panic attacks, and although I'm quite irritable once they wear off and do have suicidal thoughts some, I know it's not the kpins (since I only take them on a need-to instead of a daily basis). Also, I take 100mg Pristiq & 30 mg Vyvanse daily, but it doesn't seem to have a bad interaction with either (that I've noticed).