Only you can decide if you want to medicate it or just accept it for what it is and make concessions for that time of the month.
Personally (due to a lot of allergic and adverse reactions) I don't like to medicate for any reason unless absolutely necessary, so when I start feeling cranky, dyspeptic, weepy, and crabby, I tend to withdraw from the company of others until after I've started and am feeling better.
Of course, I still have to go to work and have to constantly remind myself that YES, this is what's going on, and NO I cannot take it out on others.
Hope you find what works best for you whatever you decide to do!