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_Sky said:
Really? I just asked if anyone knew about it. I am going to begin it Monday, if they've approved it. It is melatonin... in prescription form. I am most worried about the bad dreams that melatonin causes. What dose did you try? How long did you "sleep" totally?

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HI Sky!

Just wanted to post some information about Rozerem and how it works - because it's not just like melatonin. ROZEREM (ramelteon) is a melatonin receptor agonist - which means it attaches to specific melatonin receptor sites in the brain - "acting" like melatonin in a way. Specifically it targets M1 and M2 receptor sites. It's supposed to be taked on an empty stomach because food greatly interferes with its absorbtion - so it takes longer to work basically.

Also I've read that it should NOT be taking in combination with fluvoxamine (LUVOX) - because doing so impairs the elimination of Rozerem and greatly increases blood levels. It does not effect serotonin, norepinephrine, dopamine or GABA receptors, and it works in a part of the brain NOT associated with dependency & addiction. Apparently it's not supposed to produce any "hang-over" effects the next day and you can stop it without worry of rebound insomnia or withdrawal.

They have a great website that has a lot of useful information:

http://www.rozerem.com/

I haven't heard of anyone using this med yet - so I'm eager to hear from those who have tried it (I've got terrible insomnia).

Hope this helps!!

Jerry :-)