Just be yourself. Talk about the same stuff you always did. If you are close to your uncle and feel O.K. about it, ask him about treatments and how they are making him feel. Is there anything you can do to help out?

But don't hide from it.

Oh. And don't forget to ask your Aunt or any family member who is the primary care giver if they need anything. That person spends a great deal of time being there for your uncle. It is a hard job. Make sure they get a break to go shopping or out to lunch. It is important that their life continues to include non-cancer related events.