I took Zoloft on the max dosage for 3 years. It helped a little with the anxiety stuff. Had no depression prior. It stopped working. I fell down in a very deep depression for 3 years when I quit it, and I always thought my brain would go back to normal sooner or later. It didn't.

Now I'm on a low dosage of Luvox, that is so much more efficient for me. I wish they had started with this for me. But it became an unpopular med and wasn't longer pushed by drug companies after it became an orphan med.