Eww...I have a lot of trouble with this one. Never thought of it as SI or non-compliance. I frequently will change my meds around...change doses, skip doses, try different things and not tell my doc. I keep all my prescriptions that I've ever tried. I get very very scared of side effects and I panic at times that the meds are doing something weird to me. Also, I hate being a zombie and not being able to concentrate. My mind used to be very sharp. I've been on anti-depressants for the past 28 years and my brain feels like mush now. Also, I don't feel like the docs listen to me or know what they're doing. I'm taking a leap of faith with my new doc, now, and trusting him and doing exactly as he says. I'm not sure how long I'll give him, though.