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I think like what seems like anything else with psych meds, it really depends on the person. I didn't personally notice a major difference until 100mg, though that could have been because I hit a mixed episode while still on a low dose of the stuff (50mg).
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dx: bipolar I - lamictal 150mg/risperdal 3mg/klonopin .5mg
"Neither a lofty degree of intelligence, nor imagination, nor both together go to the making of genius. Love, that is the soul of genius."
--Wolfgang Amadeus Mozart
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