After years of living with extreme anxiety and panic disorder, with all of the other Bipolar symptons, which severely impacted my quality of life, I got a Psychiatrist that was willing to treat my panic disorder and anxiety. I take 1 mg of Klonopin 4x a day and have for over 10 years. I have never had to up the dosage, and have never had a panic attack since I started the Klonopin. I still get anxiety now and then but it doesn't keep me from going places and having a better quality of life. About 7 years ago, I was put on Seroquel, and that has been a life saver. I now get a full nights sleep most nights, and my moods have leveled out so the word extreme does not enter my cycles. Just my story not a opinion.