Thread: Roll call
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Old Apr 22, 2012, 07:40 AM
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costello costello is offline
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Member Since: Dec 2010
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Here and doing ok.

Took niacin at bedtime last night. That stuff knocks me out. I also seem to remember my dreams better. (Last night I was dreaming about spending money I didn't have - i.e., credit card. Too much like real life for my taste. ) Turns out my son did have the flush response to the niacin night before last. It just took an hour and 10 minutes to start. I was in bed by then. Last night I took the niacin with dinner, and I had a delayed and milder flush reaction too. That's a relief. My son and I didn't have such different reactions after all.

As I understand it, people with sz tend to have no or a reduced flush reaction to niacin. The flush is caused by the release of prostaglandin d2 (PGD2) from the skin. PGD2 is made of arachidonic acid (AA) which is one of the most abundant fatty acids in the brain. People with sz tend to be low on AA for some reason. I'm not sure if it's due to lack of AA (or omega 6 which the body can turn into AA) in the diet or if people with sz have problems metabolizing the omega 6 to AA. If it's a diet problem, I can do something about that. But if he's simply not making AA from omega 6 for some reason, I can't fix that.

Fortunately it seems he did have the flush, so evidently he does have AA.

(BTW, newtus, if you're reading this, the more I know about the essential fat acids and phospholipids, the more I worry about you and your diet. You need fish or fish oil. You've said you're vegetarian or vegan. You might see a dramatic change in your mental health just from adding fish oil.)
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Thanks for this!
cybermember, lil-angel-wings, Tsunamisurfer