I have been on ativan 1mg twice daily for four years it does relax me enough but I still get anxiety and panic breakthroughs a lot but the ativan works for a little while, I think that my body has started getting immune to its sedative affect. I take Depakote for my Bipolar and I ask my pdoc if it helped with anxiety and panic because I had read that it does and she said it really doesn't help that much she said the drug companies say a lot of the medicines are good for things and they really don't help at all, I am just repeating what she told me, I think that it does help some though since she raised the Depakote level I am taking my nerves have been getting better.