It may be possible to go without meds, but at this point in my life, I can't. My pdoc is very supportive of minimal med use and emphasizes self-care including alternative treatments such as meditation. We are hoping to get off the anti-depressant entirely, but who knows about the mood-stabilizer. I think he would support a reduction experiment at some point in time, though I am not ready now when I am going back to university. I do still cycle though, and I want it that way. My goal is to cycle within the bounds of functionality and that's where I am. I don't know what "normal" is anyway.