Wellbutrin affects dopamine and norepinephrine. Abilify works on dopamine and serotonin. I am of the mind we are all not text book cases. So even though your pdoc believes you on the best med combo, clearly it's not working or you would be feeling much better. Perhaps you might need a more serotonin selective med to combat your depression (Lexapro comes to mind). I hope your pdoc will let you give it a try.