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PrincessHarHar said:
Hey yall, 3 weeks ago I started seeing a new pdoc... She put me on Abilify 5mg, then I had to increase to 10mg as the 5mg werent doing anything for me... I feel much better on it through-out the day but at night things get outta control... I would call and ask my doctor but they are closed till Monday... Any suggestions? Should I take 5mg at night and 5mg during the day?

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Hi!

I did a little research and found that Abilify has a half-life of approximately 75 hours - which means after 75 hours, half the medication is still in your blood - basically. So, it's unusual that you'd be feeling it wear off by night. It would help to know what p[ositive effects yoru receive from it and if you feel these positive effects are wearing off by night. The dosing rage is 10-15mg/day. Are you feeling more anxious at night? more depressed at night? There are depressives who get more depressed in the evening rather than the morning - so It may be that the med hasn't had the time to fully cover your depressive symptoms - as it takes at least 2 weeks to reach a steady plasma state.

If your doctor is not available - it may be helpful to call your pharmacist and ask if it's possible to split the dosages into 5mg & 5mg.

I hope this helps.

Jerry