I'm on Wellbutrin XL. It did make me extremely anxious and maybe a bit manic definitely euphoric at first but, I stuck with it and adjusted well except I still don't sleep as much as I'd like without Seroquel and my appetite is terrible except when I get my much loved Seroquel munchies. Apparently Wellbutrin is less likely than an SSRI or SNRI to cause mania.

SSRIs caused terrible things for me. It was Zoloft made me psychotic, not that I hadn't ever experienced psychotic symptoms before, but I wasn't when I started Zoloft and when I stopped taking it, I was fine. I didn't bother with SNRIs and going forward I will refuse either.

I really liked Remeron. I took that with Prozac for awhile. Remeron had me so hungry! I love meds that give me an appetite! I'm very thin so no worries about a bit of weight gain and I love eating!

My only major complaint with Wellbutrin is the appetite loss. It has worked to keep me from becoming seriously depressed.