I don't think that relationships and bipolar Dont work... I think that there are people who are not bipolar who simply are not capable of handing or understanding or simply having the ability to be with someone who is bipolar.

I am wondering though.... you say you have known her for 10 years... Have you had bipolar symptoms that whole time or are they new? Have they gotten worse? I'm just curious what has changed from when you met to how things are now.

None of us will be able to tell you if there is hope for saving your marriage because none of us know whether your wife is willing to deal with the symptoms that come with bipolar.

Have you tried Marriage Counseling or even brought her with you to your therapy sessions?