I was curious as to if anyone else has experienced weight gain with medication like I have. In my case, I gained 15 pounds right after starting medication (lithium) very quickly. I gained this weight over the course of just a few short months and the 15 pounds was all I gained. Here we are a year and a half later and that weight has not come off. I have tried of course everything. I have lost over 50 pounds twice during my life so dieting is not foreign to me. Has anyone else had experience with gaining weight with their medication?