If it's an alpha-blocker, *and* it's being recommended for PTSD, then I imagine something like this......somebody was prescribed this drug for its main indication, hypertension (constant high blood pressure), and they said to the doctors that it had also had this other effect, to calm their PTSD symptoms. Okay, so this is an off-label use of the drug. That does not mean anything at all. It's a doctor using an FDA approved drug as a tool to help you feel more comfortable. We know that noradrenaline is involved in PTSD. We know there is an adrenal component to the fright response. It makes sense that PTSD people have got altered alpha receptors. This drug alters them back again. Hopefully.

As to side effects, read the first paragraph on this page: http://www.rxlist.com/cgi/generic3/prazosin_ad.htm

The side effects in the text parts of that page seldom happen. But, they could give you a feeling for a theme. When I read the list, I think "flu-like", yucky feeling. Hopefully, that will pass as your body re-sets/adjusts itself to having the drug inside it on a daily basis.

Lar