I also agree. The older I get the more severe my mania is. Just last week I had an episode. My doc. Has added another mediciine to what i'm already taking. The thing is I was stable for a long time. Now my doc. tells me it could take 4or more months to stabilize again. It's really hard for me because after taking a medicine for so long my body becomes ammune to it. Also I am perimenopausal. My moods at that time is really out of control. I have been diagnosed with bipolar w/manic , Anxiety w/ Panic attacks, and border line personality disorder. I am currently taking Lithium Carbonate 600mg at night and 150 mg in afternoon. Just started Seroquel XR 150 mg at night. Welbutin 200mg in morning Buspar 30mg 2xday benadryle 100mg 3xday.