I'm on it now and have been taking it for a few years. I haven had pretty good luck with it, I've just had to up the dose over the last year or so to get the same effect and AD properties. I started at 20mg and have slowly worked up to 80mg just recently. I have little to no side effects and have lost weight on it. It tends to make me a little tired, but that's it. One thing that is nice about Prozac is that if you need to stop taking it, there are really no withdrawal symptoms, as it has a long half life and leaves the body gradually. This is also a good thing in terms of what happens if you miss a dose - nothing bad happens when you miss, unlike most other meds. Hope this helps.