Hi. I really like Cymbalta. I have to take quite a high dose to notice it, but I find it very effective. It can trigger hypomania in me, if so, I monitor and adjust dose accordingly. I just have to be super vigilant & self-aware about potential mania, but I feel it's benefits far outweigh the negatives. I have little to no side-effects, maybe a little dry-mouthed & tremory, but that's about it. As far as psych meds go, Cymbalta has given me the least drama's. I really hope this helps you. Now I have the same question for you, but about Xeldox & Saphris. Have you tried them or heard much about them? They're nearly my last two options, as far as a stabiliser, & I'm really scared of side effects, especially weight gain. Thanks if you can give me any feedback. Good luck with your situation. I hope you try Cymbalta & it works as well for you as it did for me! xoxo