just wanted to add my 2 cents worth. i'm bp2, primarily manic and the last couple of years have struggled w/not being able to sleep. ambien used to work. now it doesn't. p/doc suggested low doses of seroquel for sleep and tho i'm fearful of weight gain, decided to try. (i cut a .25 mg. seroquel in fourths so i'm taking about .6mg nightly). asked the pharmacist about taking seroquel and she informed me that ambien will not remove the racing thoughts but seroquel will. so far it works like a charm and haven't seen any weight gain, tho i'm at the gym daily working out and have worked out for 30+ yrs.