Hi, I live in the Uk. I have finally found a doctor who is willing to prescribe this to me after 15 years of trying every anti depressant under the sun, which I either didnt react particularly well to or gave me some sort of sexual side effect. It isnt licensed for use in patients with depression in the Uk and is only available as Zyban prolonged release and licensed for use as a smoking cessation aid. However your doctor can presribe this to you if he/she sees fit although this is risky for them as it isnt a licensed med for depression here. I had my first 150mg tablet earlier. I was expecting some sort of side effect on taking it after reading stories of other people who have used it, but nothing so far. I recently stopped taking duloxetine and venlafaxine which are SNRI's and make you feel a bit weird instantly on taking them for the first few weeks. I am going to stay on 150mg for a week then move up to 300mg. I will let you know how I get on. Hope this helps, I have found it hard to find any info myself on this subject before being prescribed it myself.