Hi-
Yes i have tried benadryl for panic attacks. it doesnt work as well as the med your taking or xanax but it defintely helps at least in my case. It just kind of makes you relax and makes you feel tired -it sort of calms the fight for flight reponse when your having an anxiety attack, just make sure you don't take too much of it at once, or you'll fall asleep...good luck!!