A woman's cycle can affect medications due to the hormonal changes, and 3 days is not a very long time for the effects to stabilise. Some medications do take a week or two to take effect and side-effects to settle.

You said that her doctor is gone tomorrow but could she call the office and just check with them or another doctor at the practice about the risks? I would be hesitant to stop any medications so quickly as it can take time to work effectively, and depending on the dose can be dangerous to stop again without monitoring, especially when it comes to antidepressants.