There is a possibility that it could have something to do with the meds, or also be situational. I know persoanlly when I was still using medications that over time my body began to compensate for the drugs and they needed to change my doses and form of medications as my body didn't accept them properly any more.

If you can, I would be talking to your pdoc about what you are feeling. They should be able to help you determine whether it is something with your medications or not, and if so help you to modify your doses.