My friend described me as a hyperactive cheerleader when I was on just Wellbutrin for a year. They had me on it more for depression than anything, cause I was suicidal so that was their number one concern. Now I'm on a low dose of it to help up my mood and counteract the 200mg Zoloft I take daily for anxiety. I couldn't handle Prozac, made me puke on even a quarter dose. Zoloft has helped immensely with my anxiety, but major fatigue, sexual side effects, and tremor side effects came with it.