Hi. I'm new to this forum but have something to say about this. It's my most passionate topic! I was being treated - unsuccessfully - for borderline personality disorder/bipolar II for 3 years when someone (not my Psych) finally suggested I have my thyroid tested. (BTW, a good Psych should know to test this! Mine didn't.) My primary Dr. diagnosed me as subclinical hypothyroid in Oct. 2009. Of course, I had no idea what that meant. I mean, I knew I was high and low all the time but the Psych just kept adjusting my anti-anxiety meds, my sleeping meds, my mood stabilizers, etc. Nothing seemed to make me feel better. When I reviewed all the symptoms of being hypothyroid and I realized that many symptoms of hypo and bipolar II are the same. I felt like there was finally hope for me. A "fix" if you will. I began taking Syntheroid then Syntheroid + Cytomel and now am taking 2 grains of Nature Thyroid every day @ the same time - rain or shine My levels are tsh levels are closer to 0 than the Western accepted level of .3 and my Dr. and I monitor this regularly so I don't dip over to becoming hyperthyroid. This is obviously not something one should ever do without a Dr. monitoring but I believe there is a strong connection between thyroid and bipolar and have an article about it you might find interesting. I have seen a huge, life changing difference in my ability to manage my moods, sleeping schedule and energy. My family no longer walks on eggshells when I walk into a room. Previous to the thyroid meds, you never knew which me you'd get. Happy me, sad me, hyper me, mad me. You get it. Anyway, check out this article. Maybe it's something new to discuss with your Dr's. psycheducation.org / thyroid/ HighDose.htm