I would be happy and honored to take my wife's last name, provided that would be okay with her. The side of the family I take my last name from is far distanced from me, and part of me thinks it almost inconsiderate to ask her to take a last name that means zilch to me.
But I'm not overly picky about it. Whatever makes her happy, I'm happy with. I've got a rather long time before this is even an issue for me anyway.