Eliza Jane hit the nail on the head. Plans. Maps. Decisions. You don't necessarily have to stick to the plans like glue once you get there, but having an itinerary will give you something to look at when you get anxious about what you are going to do in this big city.

Welcome to our United States, by the way.

Also, I highly recommend the nicotine patch. I have no experience with it, but I know they used to use them in the psych hospital to keep the smokers from going crazy while...well, going crazy. If your vacation is going to be stressful, it's not the time to not smoke on top of it. Gotta make sure to get your nicotine.

Have a lot of fun here, and if you have two weeks before your trip, contact the chamber of commerce in the town/city you plan to stay for brochures to the various things to do. Or just do what EJ said, and hit the internet. It will be fun to look at all your options!