I have had hypothyroidism and depression since I was 16. I only take Synthroid for my thyroid. I've gone through MANY anti depressants and nothing seems to work all that well. Yesterday I came across a girls blog, she has hypothyroid and bipolar. She takes T3 for her thyroid and says it helps with her depression. Now I'm curious and wondering if that would help me and if I could get my doc to order labwork to check my T3 levels. My Psych doc is adamant that we do all we can for my thyroid since it can cause depression so maybe this would help. Any thoughts or experience with this?