Although I support the use of medical marijuana in appropriate cases, it's known to make bipolar worse.

I'm thinking that sometimes, what seems to be migraine may be, in actuality, a form of trigeminal neuralgia. This is a condition of the trigeminal nerve (one of the 12 cranial nerves) which can affect the eye and produce blinding pain on one side of the head and face, much like migraine.

I had one patient who'd had it for over 20 years and never got diagnosed properly; she'd been to every pain specialist in the area and gotten the same song-and-dance you did. The only reason I got suspicious was because my 30-year-old daughter has it, along with chronic 'migraines'. So I asked the patient's MD to consider using Neurontin to see if this would treat the pain, and within a couple of weeks of starting the medication, the woman said she was pain-free......and as far as I know, she stayed that way.

So.......it's a longshot, but what have you got to lose by checking this out? (Unless of course, you've already been down that road and it was ruled out.)