Hi hopscotch....Wow it sounds like you've been through a lot. My heart goes out to you. I wish I had something helpful to say regarding the medication issue, but I'm afraid all I can really say is that I've been where you are, or somewhere similar, anyway. Although I know I haven't been through as much as other people have as far as trying endless meds (lack of insurance has not allowed that).....I have been on and off of some, (plus a lot of "natural" supplements....and nothing has worked for me so far. I've been off of everything for quite some time now. As you mention, there are definitely risks involved with trying new options, and yet there is also that idea that SOMETHING might actually make a difference. Although I really can't afford the out-of-pocket cost at this time, I'm also feeling like I should probably try again. Wishing both of us good luck in figuring all of this out......Take Care.