I have to take Lamictal in both the morning and at night for some reason, even though it makes me somewhat drowsy. My pdoc is easy to get along with, but he was pretty insistent that I divide the 200 mg dose, so I just take it the way he told me and drink LOTS of coffee. The Celexa I take in the morning because it would keep me awake half the night if I were to take it then. Your mileage may vary.