I had constant med adjustments for 7 years. I never really found anything that worked long term.

I wonder if your wife communicated out of concern poorly or with frustration. I probably wouldn't be very receptive to that either, not off the bat. Do you think there is any truth to it? And do you think maybe the two of you could sit down and have a talk, a calm talk?

I think what I would probably do is " Karen, I really need to talk to you about something..... when this was said... I feel like.... How can we fiqure this out together?" ect. You get my drift. Hopefully she would be open to talking about her feelings too and maybe you two can come up with some ways to support how you cope with stress, and some understanding of why you get those adjustments.

I don't know you or your wife, so not for me to say. But I know my bf does not always communicate well, nor do I. But after a good talk, a friendly loving talk we can usually come to agreement and solutions. I wonder if she is just concerned and frustrated and it is coming out as kinda mean?