Two antidepressants is not uncommon. Prozac is an SSRI, and it has a good track record. Wellbutrin works on two other neurotransmitters, norepinehprine and dopamine. I do hope that this combination works well for you. I was on wellbutrin alone, and it worked fairly well, and fairly quickly. Though I've never been on Prozac, folks have told me that it works. In my exprience as a clinician, several of my psychiatrist friends have told me that adding an additional antidepressant can "jump start" the process to beating this illness. Best to you George.