I had a low sex drive before meds. Alcohol made a huge difference, VERY friendly indeed. But alcohol is not the way to go. I now take zoloft (200 mg) Sex drive, whats that? GONE I have zero sex drive. But I don't get along w/ my H either so it doesn't bother me. He can have it when he wants it w/in reason. It's just not great for me. He doesn't complain, but he's not the one taking the meds.