I don't know if this was on your list. I take Xanax to sleep. Also have a friend with treatment-resistant depression. She's had ECT (no result there, but it has helped another friend a lot). She's researching other options like VNS (I believe it's called) where they put a device in your neck & stimulate it. There are other treatments that are coming into the forefront for this. Sorry I can't remember all that she is looking into, but maybe a search of "treatment resistant depression" would help.

I can imagine the frustration & hopelessness you must feel. I've been so lucky to find meds to treat my bipolar. I wish you the best. Do you have a pdoc that is up on the latest stuff? Mine was & got me onto new meds "off label" early that worked.