Hi Livebythesea.....I'm really sorry you haven't found an antidepressant that has worked right for you. I do not want to be discouraging at all, but just so you know you're not alone in your frustration, I have been on several meds, and have not really (yet) discovered the answer. (I've been on Prozac, Paxil, Effexor, Cymbalta, and Zoloft, plus a lot of "natural" supplements.) I've actually been off of everything for a while now, but am thinking I need to see a good psychiatrist and dive into the med pool again I hope that both of us are able to find something that will help. Best Wishes ~whimsy