My high-stress job actually is less of an issue when I'm depressed than when I'm manic. Depressed, I'm generally avoidant and I just hole up in my office and get the paperwork done. Manic, I'm bouncing off the walls, can't concentrate for squat, and tend to make bizarre statements that I later don't recall (or so my boss said when I threw my big wingding early this summer). I'm very fortunate in that he knows about my diagnosis and works with me when he sees that I'm getting strung out.