Chronic pain brings me down lower than the bipolar does. I don't deal well with it at all, I am glad my runs in cycles, so I do get a break from it in between, hopefully it will be a thing of the past. Asthma here too BipolaRNurse, and allergies, lots of them, I have Polymorphus Light Eruption (PMLE), ... Solar Urticaria that one I would willing trade, the rest are not too bad.