I've done well with it since starting it back in March. It did throw me into hypomania when the dose went from 150 to 200 mg, and then I went from there straight into a full-blown manic episode. It took adding Zyprexa to get that under control, and then my pdoc decreased the Celexa from 20 to 10 mg and I've been pretty good since that time. The only real issues I've had were when we tried to discontinue the Celexa.......that got really ugly! I also flipped right into hypomania again when we tried going off Zyprexa, so I really do need all of it along with Lamictal to pull everything together.