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almostangela said:
I used to take St. John's wort until I discovered I had Grave's disease (hyperthyroid) and the Doc told me to stop immediatley. It is one of the items that is suspect to bringing out the dormant disease. I heard that too much is toxic so I would tread carefully on that herb

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There is no known toxic threshold for St. John's wort. That's not to say that an individual could not suffer from taking an excess, but it is not considered to be toxic in the normal sense of the word. Adverse reactions tend to be: headaches, gastrointestinal distress, and sun sensitivity. Over the counter meds often are sufficient to treat the first two, and the latter can be addressed with sunscreen.

SJW does affect the half-life of other medications. The best way to think of SJW is that it does the opposite to grapefruit juice, but to the same meds which are sensitive to grapefruit intake.

Lar