I've been on lamictal for about a month now, they step u up on it very slowly bc there is one dangerous but rare side effect- a rash that can be fatal! I am just about a week into stepping up from 25 mg to 50. Through the 25 mg wks I really didnt feel any different but since I moved up to 50 I am feeling so much better! I have been thru hell the past 4 days and I have handled it so much better than the "normal me" would have. But like Blue I said, its all in your personal chemical make up and what wks well for one person may not for you. Best of luck! Keep us informed.